Organocatalytic enantioselective synthesis of metabotropic glutamate receptor ligands.
نویسندگان
چکیده
(R)-Proline catalyzes the amination reaction of functionalized indane carboxaldehydes and allows for the efficient enantioselective synthesis (>99% ee) of the metabotropic glutamate receptor ligands (S)-AIDA and (S)-APICA. [reaction: see text]
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ورودعنوان ژورنال:
- Organic letters
دوره 7 18 شماره
صفحات -
تاریخ انتشار 2005